Pain is always an unpleasant sensation and distress which caused by intense or damaging stimuli. It is feeling that trigger in the nervous system. Pain can be minute to severe and can last for long time. It affects each and every person life by interfering in their daily routine. Having pain in the body can lead to negative attitude and mood swing.  You may feel pain in one part of your body such as back pain, abdomen, and chest or sometime in the whole body such as muscle ache. Ultram is a medication that helps in the treatment of pain. 

 

 

ULTRAM: an effective medication to overcome all kind of pain.

Tramadol is a generic name for prescription pain reliever under the brand names ultram, which used to treat postoperative, dental care and acute musculoskeletal pain. It comes under the category of narcotics and analgesics. Food and drug administration approved this drug in 1995. FDA has also approved the generic version of this drug in 2002. Tramadol is not a non-steroidal anti-inflammatory drug. It does not increase the risk of stomach ulceration and internal bleeding.

 


MECHANISM OF ACTION:

Ultram binds to the receptors in the brain which is important for transmitting the signal of pain from the body to the brain. It has dual mechanism of action.

Opioid activity: It is due to low affinity binding of the parent compound and higher affinity binding of O-demethylated metabolite M1 to mu-opioid receptors.

Non-Opioid activity: Ultram inhibits reuptake of norepinephrine and serotonin which inhibits pain transmission.

 

Ultram available in different dosage:  50mg, 1oomg and 200mg. It is available in several forms: tablets, orally, capsule and suspension. This medication is taken by mouth as directed by your physician. Swallow the tablet whole to avoid exposure to a potentially fatal dose.   Usually ultram is taken every 4 to 6 hours as needed for pain relief.

Ultram is rapidly and completely absorbed after oral administration and the mean absolute bioavailability of 100mg oral dose is 75%.   It is taken with or without food. Ultram and its metabolites are mainly excreted via kidney.

 


Never take ultram in large amount and for longer time than prescribed.

Ultram should not be taken by patients, who are hypersensitivity to it or any other ingredient present in it.  It should not be taken along with alcohol, hypnotics, narcotics, opioids, centrally acting analgesics and psychotropic drugs because it can worsen central nervous system and respiratory depression in the patient and can lead to dangerous side effect and some time death.

 

Special precaution should be taken by patient facing mild to severe hepatic impairment, history of sensitivity to phenylketones, concurrent use of monoamine oxidase, elderly patient and Pregnant and breast feeding women as it can cause some side effect and breathing problem.  

 

 Taking ultram with the combination of other drugs can make you sleepy or slow your breathing. Drug such as warfarin, antifungal medicine, lithium, lanoxin, paxil, pexeva, zoloft and many more. So it is better to avoid intake of ultram with these medications.

 


Buy ULTRAM at affordable price form any pharmacy or online site to reduce your pain.