It is a term which signifies a fact that males are not able to maintain a sufficient erection at the time of physical intercourse with their partners. Maintaining a successful erection actually signifies erection in various parts of the body such as brain, nerves, hormones, muscles and heart. Anything that interrupts this system pathway is called as impotence. Some people may find it guilty when they are known about this fact that they have the problem of erectile dysfunction, and they might sometime fear to talk about this to their doctor. At this very particular time, Cenforce is most commonly suggested to be taken and by doctors too in order to make a satisfying erection.

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How does Cenforce work?

Cenforce contains Sildenafil as the major active ingredient that inhibits the cGMP-specific phosphodiesterase type 5 (PDE5) which is responsible for degradation of cGMP in the corpus cavernosum located around the penile. Penile erection during sexual stimulation is caused by increased penile blood flow resulting from the relaxation of penile arteries and corpus cavernosal smooth muscle. This response is mediated by the release of nitric oxide (NO) from nerve terminals and endothelial cells, which stimulates the synthesis of cGMP in smooth muscle cells. Cyclic GMP causes smooth muscle relaxation and increased blood flow into the corpus cavernosum. The inhibition of phosphodiesterase type 5 (PDE5) by Sildenafil enhances erectile function by increasing the amount of cGMP.

Dosage Information for Cenforce:

Cenforce is available in the strength of 25mg, 50mg, 100mg, 120mg, 150mg and 200mg.  This medication is to be taken orally with sufficient amount of water 30-40 minutes before the planned intercourse.  Do not crush or chew the tablet. Swallow the tablet as a whole. However, some side effects are likely to occur by using this medication such as  fever, headache, nausea, vomiting and painful erection.

Warnings & Precautions:

There are some precautionary measures to be kept in mind while using Cenforce such as; Alcohol consumption should be avoided in order to avoid the adverse effects; Caution is advised while using this medication along with alpha blockers as it may cause sudden decline in blood pressure; avoid use of grapefruit juice while using this medication as it can cause severe adverse effects; patients suffering from serious cardiac disorders should use this medication with extreme caution as sexual activity is associated with potential cardiac risks; patients suffering from sickle cell anemia and multiple myelomas should use this medicine only after the consultation with the doctor; not recommended for individuals below 12 years of age.

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