Medical abortion involves the use of some tablets for terminating the pregnancy while surgical method involves the use of surgical instruments and anesthesia.This method involves vacuum aspiration and evacuation for removing the fetus from the uterus of the mother. In earlier times, the surgical procedure was done using these surgical instruments and anesthesia but this method of abortion was the really painful procedure. With the development of medical science and technology, there are pills/tablets available in the market which can perform the abortion just by the intake of these. Various advantages of medical abortion with MTP includes:

  • Helps in sustaining privacy
  • No requirement of doctor or any surgical process
  • No obstruction of future pregnancy
  • Can be done at home just by intake of some pills

 

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Mechanism of action for MTP Kit:

MTP Kit contains Mifepristone and Misoprostol as active ingredients. The anti-progestational activity of Mifepristone results from competitive interaction with progesterone at progesterone receptor sites. Based on studies with various oral doses in several animal species, the compound inhibits the activity of endogenous or exogenous progesterone. Misoprostol seems to inhibit gastric acid secretion by a direct action on the parietal cells through binding to the prostaglandin receptor. The activity of this receptor is mediated by G proteins which normally activate adenylate cyclase. The indirect inhibition of adenylate cyclase by Misoprostol may be dependent on guanosine-5’-triphosphate (GTP). Misoprostol has also been shown to increase the amplitude and frequency of uterine contractions during pregnancy via selective binding to the EP-2/EP-3 prostanoid receptors.

 

Dosage Information for MTP Kit:

MTP Kit consists of 5 tablets with an active ingredient Mifepristone and Misoprostol. For consuming this medication follow these simple steps-

  • On Day 1take a single tablet of Mifepristone 200mg orally with plenty amount of water.
  • On Day 3 take 4 tablets of Misoprostol 200mcg orally as a whole with sufficient amount of water and particularly without meals.
  • On Day 14, you should visit a nearby physician to conform the termination of pregnancy. 

 

Precautionary Measures:

  • This medication is contraindicated to be used in females below 16 years of age.
  • This medication is avoided to be used in patients having a cardiac ailment, liver or kidney damage issues and any other blood pressure related issues.
  • It should not be used with some medications such as warfarin and others that might interact with the activity of the drug.
  • Precautions to be taken after the abortion such as to avoid the intercourse for about 2 weeks of abortion and removing IUDs.
  • The Proper nutritious diet should be taken in order to recover from abortion easily.

 

 

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